l  General Information  | 
Product Name  | GW3965 HCl  | 
General description  | GW3965 HCl is a potent, selective LXR
  agonist for hLXRα and hLXRβ.  | 
Synonym  | 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-(2,2-diphenylethyl)amino]propoxy]phenyl]acetic acid; hydrochloride  | 
Purity  | ≥98.0%(HPLC)  | CAS
  Number  | 405911-17-3  | 
Formula  | C33H31ClF3NO3·HCl  | Molecular
  Weight  | 618.51  | 
Suitability  | BioReagent, suitable for cell culture, etc.  | 
l  Physical and Chemical Information  | 
Appearance  | Solid  | 
Solubility(25℃)  | DMSO  | ≥15mg/mL(warmed)  | 
Ethanol  | Insoluble  | 
Water  | Insoluble  | 
l  Biological Information  | 
Biochem/Physiol
  Actions  | GW3965 HCl is a potent, selective LXR agonist for hLXRα and hLXRβ with EC50 of 190 and 30 nM in cell-free assays, respectively.  | 
l  Storage  | 
Storage temp.  | -20℃  | 
l  Precautions and Disclaimer  | 
This product is for R&D use only, not for drug, household, or other uses.  | 
l  References  | 
1.    http://www.drugbank.ca 2.    https://ncit.nci.nih.gov 3.    https://www.ncbi.nlm.nih.gov  |