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GW3965 HCl

Product #: TS0446
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l  General Information

Product Name

GW3965 HCl

General description

GW3965 HCl is a potent, selective LXR  agonist for hLXRα and hLXRβ.

Synonym

2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-(2,2-diphenylethyl)amino]propoxy]phenyl]acetic acid; hydrochloride

Purity

≥98.0%(HPLC)

CAS  Number

405911-17-3

Formula

C33H31ClF3NO3·HCl

Molecular  Weight

618.51

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25℃)

DMSO

≥15mg/mL(warmed)

Ethanol

Insoluble

Water

Insoluble

l  Biological Information

Biochem/Physiol  Actions

GW3965 HCl is a potent, selective LXR agonist for hLXRα and hLXRβ with EC50 of 190 and 30 nM in cell-free assays, respectively.

l  Storage

Storage temp.

-20℃

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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