l General Information |
Product Name | Ethosuximide |
General description | Ethosuximide is a succinimide anticonvulsant, used mainly in absence seizures; A calcium channel blocker. |
Synonym | 3-ethyl-3-methylpyrrolidine-2,5-dione |
Purity | ≥98.0%(HPLC) | CAS Number | 77-67-8 |
Formula | C7H11NO2 | Molecular Weight | 141.17 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25℃) | DMSO | ≥25mg/mL |
Ethanol | ≥25mg/mL |
Water | ≥25mg/mL |
l Biological Information |
Biochem/Physiol
Actions | Ethosuximide is a succinimide with anticonvulsant activity. The exact mechanism of action is not entirely understood, but most likely ethosuximide exerts its effects by partial antagonism of T-type calcium channels of the thalamic neurons. This leads to a decrease in burst firing of thalamocortical neurons, which stabilizes the nerve activity in the brain and prevents seizures. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
