l General Information |
Product Name | Bardoxolone Methyl |
General description | Bardoxolone Methyl is an IKK inhibitor, showing potent proapoptotic and anti-inflammatory activities. |
Synonym | RTA 402, TP-155, NSC 713200, CDDO Methyl Ester |
Purity | ≥98.0%(HPLC) | CAS Number | 218600-53-4 |
Formula | C32H43NO4 | Molecular Weight | 505.69 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25℃) | DMSO | ≥15mg/mL |
Ethanol | Insoluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | Bardoxolone Methyl is an IKK inhibitor, showing potent proapoptotic and anti-inflammatory activities; Also a potent Nrf2 activator and nuclear factor-κB (NF-κB) inhibitor. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
