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JSH-23

Product #: TS0390
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Details

l  General Information

Product Name

JSH-23

General description

JSH-23 is an inhibitor of NF-κB transcriptional activity.

Synonym

4-methyl-1-N-(3-phenylpropyl)benzene-1,2-diamine

Purity

≥98.0%(HPLC)

CAS Number

749886-87-1

Formula

C16H20N2

Molecular Weight

240.34

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25℃)

DMSO

≥45mg/mL

Ethanol

≥15mg/mL

Water

Insoluble

l  Biological Information

Biochem/Physiol  Actions

JSH-23 is a diamine that is 1,2-phenylenediamine carrying a methyl substituent at position 4 and a 3-phenylpropyl substituent at position N1. JSH-23 is an inhibitor of NF-κB transcriptional activity with IC50 of 7.1 μM in RAW 264.7 cell line.

l  Storage

Storage temp.

-20℃

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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