l General Information |
Product Name | BAY 11-7082 |
General description | BAY 11-7082 is a NF-κB inhibitor. |
Synonym | (E)-3-(4-methylphenyl)sulfonylprop-2-enenitrile; BAY 11-7821 |
Purity | ≥98.0%(HPLC) | CAS Number | 19542-67-7 |
Formula | C10H9NO2S | Molecular Weight | 207.25 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25℃) | DMSO | ≥35mg/mL |
Ethanol | ≥5mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | BAY11-7082 is a NF-κB inhibitor, inhibits TNFα-induced IκBα phosphorylation with IC50 of 10 μM in tumor cells. Also inhibiting components of the ubiquitin system. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
