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MG-132

Product #: TS0373
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Details

l  General Information

Product Name

MG-132

General description

MG132 is a potent cell-permeable proteasome and calpain inhibitor.

Synonym

benzyl N-[(2S)-4-methyl-1-[[(2S)-4-methyl-1-[[(2S)-4-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]carbamate

Purity

≥98.0%(HPLC)

CAS Number

133407-82-6

Formula

C26H41N3O5

Molecular Weight

475.62

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25℃)

DMSO

≥50mg/mL

Ethanol

≥20mg/mL

Water

Insoluble

l  Biological Information

Biochem/Physiol  Actions

MG132 is a potent cell-permeable proteasome and calpain inhibitor with IC50s of 0.1 and 1.2 μM for the inhibition of proteasome and calpain, respectively.

l  Storage

Storage temp.

-20℃

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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