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Mdivi-1

Product #: TS0319
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Details

l  General Information

Product Name

Mdivi-1

General description

Mdivi-1 is a selective cell-permeable inhibitor of mitochondrial division DRP1 and mitochondrial division Dynamin  I.

Synonym

3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanylidene-1H-quinazolin-4-one

Purity

≥98.0%(HPLC)

CAS Number

338967-87-6

Formula

C15H10Cl2N2O2S

Molecular Weight

353.22

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25℃)

DMSO

≥50mg/mL

Ethanol

Insoluble

Water

Insoluble

l  Biological Information

Biochem/Physiol  Actions

Mdivi-1 is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 μM.

l  Storage

Storage temp.

-20℃

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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