l General Information |
Product Name | PD98059 |
General description | PD98059 is a non-ATP competitive MEK inhibitor. |
Synonym | 2-(2-amino-3-methoxyphenyl)chromen-4-one |
Purity | ≥98.0%(HPLC) | CAS Number | 167869-21-8 |
Formula | C16H13NO3 | Molecular Weight | 267.28 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25℃) | DMSO | ≥10mg/mL(warmed) |
Ethanol | Insoluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | PD98059 is a non-ATP competitive MEK inhibitor with IC50 of 2 μM in a cell-free assay, specifically inhibits MEK-1 mediated activation of MAPK; does not directly inhibit ERK1 or ERK2. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
