l General Information |
Product Name | Cryptotanshinone |
General description | Cryptotanshinone is a STAT3 inhibitor. |
Synonym | (1R)-1,6,6-trimethyl-2,7,8,9-tetrahydro-1H-naphtho[1,2-g][1]benzofuran-10,11-dione |
Purity | ≥98.0%(HPLC) | CAS Number | 35825-57-1 |
Formula | C19H20O3 | Molecular Weight | 296.36 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25℃) | DMSO | ~5mg/mL(warmed) |
Ethanol | ~1mg/mL(warmed) |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | Cryptotanshinone is a STAT3 inhibitor with IC50 of 4.6 μM in a cell-free assay, strongly inhibits phosphorylation of STAT3 Tyr705, with a small effect on STAT3 Ser727, but none against STAT1 nor STAT5. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
