l General Information |
Product Name | STF-62247 |
General description | STF-62247 is a molecule targeting VHL-deficient renal cell carcinoma that induces autophagy. |
Synonym | N-(3-methylphenyl)-4-pyridin-4-yl-1,3-thiazol-2-amine |
Purity | ≥98.0%(HPLC) | CAS Number | 315702-99-9 |
Formula | C15H13N3S | Molecular Weight | 267.35 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | ~3mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | STF-62247 is a molecule targeting VHL-deficient renal cell carcinoma that induces autophagy. STF-62247 shows selective toxicity and growth inhibition of renal cells lacking VHL; 25-fold greater sensitivity observed for cells with VHL deficiency compared to wild-type (VHL+). |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
