l General Information |
Product Name | Fasudil (HA-1077) HCl |
General description | Fasudil is a potent and selective inhibitor of Rho kinase. |
Synonym | 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline;hydrochloride |
Purity | ≥98.0%(HPLC) | CAS Number | 105628-07-7 |
Formula | C14H17N3O2S·HCl | Molecular Weight | 327.83 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25℃) | DMSO | ~5mg/mL |
Ethanol | Insoluble |
Water | ≥50mg/mL |
l Biological Information |
Biochem/Physiol
Actions | Fasudil, a potent and selective inhibitor of Rho kinase, displays less potent inhibiton over PKA, PKG, PKC and MLCK with Ki of 1.6, 1.6, 3.3, and 36 μM in cell-free assays, respectively. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
