l General Information |
Product Name | QNZ (EVP4593) |
General description | EVP4593 shows potent inhibitory activity toward both NF-κB activation and TNF-α production with IC50 of 11 nM and 7 nM in Jurkat T cells, respectively. |
Synonym | 4-N-[2-(4-phenoxyphenyl)ethyl]quinazoline-4,6-diamine |
Purity | ≥98.0%(HPLC) | CAS Number | 545380-34-5 |
Formula | C22H20N4O | Molecular Weight | 356.42 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25℃) | DMSO | ~5mg/mL(warmed) |
Ethanol | Insoluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | EVP4593 shows potent inhibitory activity toward both NF-κB activation and TNF-α production with IC50 of 11 nM and 7 nM in Jurkat T cells, respectively. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
