l General Information |
Product Name | Belnacasan (VX-765) |
General description | Belnacasan is a potent and selective inhibitor of caspase-1. |
Synonym | (2S)-1-[(2S)-2-[(4-amino-3-chlorobenzoyl)amino]-3,3-dimethylbutanoyl]-N-[(2R,3S)-2-ethoxy-5-oxooxolan-3-yl]pyrrolidine-2-carboxamide |
Purity | ≥98.0%(HPLC) | CAS Number | 273404-37-8 |
Formula | C24H33ClN4O6 | Molecular Weight | 509 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25℃) | DMSO | ≥50mg/mL(warmed) |
Ethanol | ≥50mg/mL(warmed) |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | Belnacasan is a potent and selective inhibitor of caspase-1 with Ki of 0.8 nM in a cell-free assay. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
