l General Information |
Product Name | UMI-77 |
General description | UMI-77 is a selective Mcl-1 inhibitor. |
Synonym | 2-[4-[(4-bromophenyl)sulfonylamino]-1-hydroxynaphthalen-2-yl]sulfanylacetic acid |
Purity | ≥98.0%(HPLC) | CAS Number | 518303-20-3 |
Formula | C18H14BrNO5S2 | Molecular Weight | 468.34 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25℃) | DMSO | ≥93mg/mL |
Ethanol | ≥93mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | UMI-77 is a selective Mcl-1 inhibitor with Ki of 490 nM, showing selectivity over other members of Bcl-2 family. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This
product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
