l General Information |
Product Name | CGI1746 |
General description | CGI1746 is a potent and highly selective small-molecule inhibitor of the Btk. |
Synonym | 4-tert-butyl-N-[2-methyl-3-[4-methyl-6-[4-(morpholine-4-carbonyl)anilino]-5-oxopyrazin-2-yl]phenyl]benzamide |
Purity | ≥98.0%(HPLC) | CAS Number | 910232-84-7 |
Formula | C34H37N5O4 | Molecular Weight | 579.69 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | ≥30mg/mL(warmed) |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | CGI1746 is a potent and highly selective small-molecule inhibitor of the Btk with IC50 of 1.9 nM. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
