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GW2580
TS0219-5MG
In-stock
79.6
- +
TS0219-10MG
136
TS0219-25MG
196
l General Information
Product Name
General description
GW2580 is a selective CSF-1R inhibitor.
Synonym
5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]pyrimidine-2,4-diamine; SC-203877
Purity
≥98.0%(HPLC)
CAS Number
870483-87-7
Formula
C20H22N4O3
Molecular Weight
366.41
Suitability
BioReagent, suitable for cell culture, etc.
l Physical and Chemical Information
Appearance
Solid
Solubility(25℃)
DMSO
≥45mg/mL
Ethanol
Insoluble
Water
l Biological Information
Biochem/Physiol Actions
GW2580 is a selective CSF-1R inhibitor for c-FMS with IC50 of 30 nM, 150- to 500-fold selective compared to b-Raf, CDK4, c-KIT, c-SRC, EGFR, ERBB2/4, ERK2, FLT-3, GSK3, ITK, JAK2 etc.
l Storage
Storage temp.
-20℃
l Precautions and Disclaimer
This product is for R&D use only, not for drug, household, or other uses.
l References
1. http://www.drugbank.ca
2. https://ncit.nci.nih.gov
3. https://www.ncbi.nlm.nih.gov
