Phone:| Tech Support:| E-mail:

GSK1838705A

Product #: TS0206
Image SKU-Pack Size Stock Price($) Quantity

Documents

Details

l  General Information

Product Name

GSK1838705A

General description

GSK1838705A is a potent IGF-1R inhibitor.

Synonym

2-[[2-[[1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-dihydroindol-6-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-6-fluoro-N-methylbenzamide

Purity

98.0%(HPLC)

CAS Number

1116235-97-2

Formula

C27H29FN8O3

Molecular Weight

532.57

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

solid

Solubility(25℃)

DMSO

≥50mg/mL

Ethanol

Insoluble

Water

Insoluble

l  Biological Information

Biochem/Physiol  Actions

GSK1838705A is a potent IGF-1R inhibitor with IC50 of 2.0 nM, modestly potent to IR and ALK with IC50 of 1.6 nM and 0.5 nM, respectively, and little activity to other protein kinases.

l  Storage

Storage temp.

-20

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

天问科技