l General Information |
Product Name | CP-673451 |
General description | CP-673451 is a selective inhibitor of PDGFRα/β. |
Synonym | 1-[2-[5-(2-methoxyethoxy)benzimidazol-1-yl]quinolin-8-yl]piperidin-4-amine |
Purity | ≥98.0%(HPLC) | CAS Number | 343787-29-1 |
Formula | C24H27N5O2 | Molecular Weight | 417.5 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | solid |
Solubility(25℃) | DMSO | ≥25mg/mL(warmed) |
Ethanol | ~4mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | CP-673451 is a selective inhibitor of PDGFRα/β with IC50 of 10 nM/1 nM in cell-free assays, exhibits >450-fold selectivity over other angiogenic receptors, has antiangiogenic and antitumor activity. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
