l General Information |
Product Name | ZM 306416 |
General description | ZM 306416 is a VEGFR (Flt and KDR) inhibitor. |
Synonym | N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine |
Purity | ≥98.0%(HPLC) | CAS Number | 690206-97-4 |
Formula | C16H13ClFN3O2 | Molecular Weight | 333.74 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | Insoluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | ZM 306416 is a VEGFR (Flt and KDR) inhibitor for VEGFR1 with IC50 of 0.33 μM, but also found to inhibit EGFR with IC50 of <10 nM. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
