l General Information |
Product Name | SB225002 |
General description | SB225002 is a potent, and selective CXCR2 antagonist with IC50 of 22 nM for inhibiting interleukin IL-8 binding to CXCR2, >150-fold selectivity over the other 7-TMRs tested. |
Synonym | 1-(2-bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea |
Purity | ≥98.0%(HPLC) | CAS Number | 182498-32-4 |
Formula | C13H10BrN3O4 | Molecular Weight | 352.144 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | ~3mg/mL(warmed) |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | SB225002 is a potent, and selective CXCR2 antagonist with IC50 of 22 nM for inhibiting interleukin IL-8 binding to CXCR2, >150-fold selectivity over the other 7-TMRs tested. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
