Product Name

L-NAME HCl

General description

L-NAME HCl an EC 1.14.13.39 (nitric oxide synthase) inhibitor.

Synonym

methyl (2S)-2-amino-5-[[amino(nitramido)methylidene]amino]pentanoate; hydrochloride

Purity

≥98.0%(HPLC)

CAS Number

51298-62-5

Formula

C⁷H¹⁶ClN⁵O⁴

Molecular Weight

269.69

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

solid

Solubility(25℃)

DMSO

≥50mg/mL

Ethanol

Insoluble

Water

Insoluble

l  Biological Information

Biochem/Physiol  Actions

L-NAME is a hydrochloride obtained by combining N(gamma)-nitro-L-arginine methyl ester with one equivalent of hydrochloric acid. It has a role as an EC 1.14.13.39 (nitric oxide synthase) inhibitor. It contains a N(gamma)-nitro-L-arginine methyl ester(1+).

L-NAME is a nive inhibitor of nitric oxide synthetases (NOS) for nNOS (bovine), eNOS (human), and iNOS  (murine), with Ki of 15 nM, 39 nM and 4.4 μM, respectively.

l  Storage

Storage temp.

-20℃

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov