l General Information |
Product Name | Apocynin |
General description | Apocynin is a selective NADPH-oxidase inhibitor with IC50 of 10 μM. |
Synonym | 1-(4-hydroxy-3-methoxyphenyl)ethanone; Acetovanillone; 4’-Hydroxy-3’-methoxyacetophenon |
Purity | ≥98.0%(HPLC) | CAS Number | 498-02-2 |
Formula | C9H10O3 | Molecular Weight | 166.17 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | solid |
Solubility(25℃) | DMSO | ≥30mg/mL |
Ethanol | ≥30mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | Apocynin is an aromatic ketone that is 1-phenylethanone substituted by a hydroxy group at position 4 and a methoxy group at position 3. It has a role as a non-narcotic analgesic, a non-steroidal anti-inflammatory drug, an antirheumatic drug, a peripheral nervous system drug, an EC 1.6.3.1. [NAD(P)H oxidase (H2O2-forming)] inhibitor and a plant metabolite. It is a member of acetophenones, a methyl ketone and an aromatic ketone. Apocynin is a selective NADPH-oxidase inhibitor with IC50 of 10 μM. |
Application | 1. Enzyme Inhibitors 2. Antioxidants 3. Anti-Inflammatory Agents, Non-Steroidal 4.Acetovanillone has been used in trials studying the treatment of Bronchial Asthma and Chronic Obstructive Pulmonary
Disease. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
