Product Name

Methylprednisolone

General description

Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties.

Synonym

(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one; Medrol; Medrone; NSC-19987

Purity

≥98.0%(HPLC)

CAS Number

83-43-2

Formula

C²²H³⁰O⁵

Molecular Weight

374.477

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

solid

Solubility(25℃)

DMSO

≥50mg/mL

Ethanol

Slightly soluble

Water

Insoluble

l  Biological Information

Biochem/Physiol  Actions

Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties. Methylprednisolone binds to and activates specific nuclear receptors, resulting in altered gene and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating  lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cell populations.

Application

1. Antiemetics

2. Anti-Inflammatory Agents

3. Glucocorticoids

4. Neuroprotective Agents

l  Storage

Storage temp.

-20℃

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov