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AMI-1

Product #: TS0142
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Details

l  General Information

Product Name

AMI-1

General description

AMI-1 is a potent and specific Histone Methyltransferase (HMT) inhibitor.

Synonym

disodium; 4-hydroxy-7-[(5-hydroxy-7-sulfonatonaphthalen-2-yl)carbamoylamino]naphthalene-2-sulfonate

Purity

≥98.0%(HPLC)

CAS Number

20324-87-2

Formula

C21H14N2Na2O9S2

Molecular Weight

548.45

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

solid

Solubility(25℃)

DMSO

≥50mg/mL(warmed)

Ethanol

Insoluble

Water

≥5mg/mL

l  Biological Information

Biochem/Physiol  Actions

AMI-1 is a potent and specific Histone Methyltransferase (HMT) inhibitor with IC50 of 3.0 μM and 8.8 μM for yeast Hmt1p and human PRMT1, respectively.

l  Storage

Storage temp.

-20℃

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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