Product Name

(-)-Epigallocatechin Gallate

General description

(-)-Epigallocatechin Gallate is a phenolic antioxidant found in a number of plants such as green and black tea.

Synonym

[(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl]  3,4,5-trihydroxybenzoate; EGCG

Purity

≥98.0%(HPLC)

CAS Number

989-51-5

Formula

C²²H¹⁸O¹¹

Molecular Weight

458.37

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

solid

Solubility(25℃)

DMSO

≥50mg/mL(warmed)

Ethanol

≥50mg/mL(warmed)

Water

≥20mg/mL(warmed)

l  Biological Information

Biochem/Physiol  Actions

(-)-Epigallocatechin Gallate is a phenolic antioxidant found in a number of plants such as green and black tea. It inhibits cellular oxidation and prevents free radical damage to cells. It is under study as a potential cancer chemopreventive agent.

(-)-Epigallocatechin Gallate(EGCG) is the main catechin extraction of green tea that inhibits telomerase and DNA methyltransferase. EGCG blocks the activation of EGF receptors and HER-2 receptors. ECGG inhibits fatty acid synthase and glutamate dehydrogenase  activity.

Application

1. Anticarcinogenic Agents

2. Neuroprotective Agents

3. Antimutagenic Agents

4. Antioxidants

l  Storage

Storage temp.

-20℃

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov