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Home > Products > Small molecule > Epigenetics > Barasertib (AZD1152-HQPA)

Barasertib (AZD1152-HQPA)

Product #: TS0117
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Details

l  General Information

Product Name

Barasertib (AZD1152-HQPA)

General description

Barasertib is a highly selective Aurora B inhibitor.

Synonym

2-[3-[[7-[3-[ethyl(2-hydroxyethyl)amino]propoxy]quinazolin-4-yl]amino]-1H-pyrazol-5-yl]-N-(3-fluorophenyl)acetamide; INH 34

Purity

≥98.0%(HPLC)

CAS Number

722544-51-6

Formula

C26H30FN7O3

Molecular Weight

507.56

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

solid

Solubility(25℃)

DMSO

≥50mg/mL

Ethanol

~3mg/mL

Water

Insoluble

l  Biological Information

Biochem/Physiol  Actions

Barasertib is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay, ~3700 fold more selective for Aurora B over Aurora A.

l  Storage

Storage temp.

-20℃

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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