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A-966492

Product #: TS0094
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l  General Information

Product Name

A-966492

General description

A-966492 is a novel and potent inhibitor of PARP1 and PARP2 with Ki of 1 nM and 1.5 nM, respectively.

Synonym

2-[2-fluoro-4-[(2S)-pyrrolidin-2-yl]phenyl]-1H-benzimidazole-4-carboxamide

Purity

≥98.0%(HPLC)

CAS Number

934162-61-5

Formula

C18H17FN4O

Molecular Weight

324.35

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

solid

Solubility(25℃)

DMSO

≥50mg/mL(warmed

Ethanol

Insoluble

Water

Insoluble

l  Biological Information

Biochem/Physiol  Actions

A-966492 is a novel and potent inhibitor of PARP1 and PARP2 with Ki of 1 nM and 1.5 nM, respectively.

Application

Poly(ADP-ribose) Polymerase Inhibitors

l  Storage

Storage temp.

-20℃

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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