Product Name

INO-1001 (3-Aminobenzamide)

General description

INO-1001 is a potent inhibitor of PARP.

Synonym

3-aminobenzamide; 3-ABA, 3-amino Benzamide, 3-AB

Purity

≥98.0%(HPLC)

CAS Number

3544-24-9

Formula

C⁷H⁸N²O

Molecular Weight

136.15

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

solid

Solubility(25℃)

DMSO

≥25mg/mL

Ethanol

≥25mg/mL

Water

Insoluble

l  Biological Information

Biochem/Physiol  Actions

INO-1001 is a potent inhibitor of PARP with IC50 of <50 nM in CHO cells and a mediator of oxidant-induced myocyte dysfunction during reperfusion.

Application

1. Neuroprotective Agents

2. Poly(ADP-ribose) Polymerase Inhibitors

3. Radiation-Sensitizing Agents

l  Storage

Storage temp.

-20℃

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov