l General Information |
Product Name | PCI-34051 |
General description | PCI-34051 is a potent and specific HDAC8 inhibitor. |
Synonym | N-hydroxy-1-[(4-methoxyphenyl)methyl]indole-6-carboxamide |
Purity | ≥98.0%(HPLC) | CAS Number | 950762-95-5 |
Formula | C17H16N2O3 | Molecular Weight | 296.32 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | Insoluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | PCI-34051 is a potent and specific HDAC8 inhibitor with IC50 of 10 nM in a cell-free assay. It has greater than 200-fold selectivity over HDAC1 and 6, more than 1000-fold selectivity over HDAC2, 3, and 10. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This
product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
