l General Information |
Product Name | NU7026 |
General description | NU7026 is a potent DNA-PK inhibitor. |
Synonym | 2-morpholin-4-ylbenzo[h]chromen-4-one; LY293646 |
Purity | ≥98.0%(HPLC) | CAS Number | 154447-35-5 |
Formula | C17H15NO3 | Molecular Weight | 281.311 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | solid |
Solubility(25℃) | DMSO | ~1mg/mL |
Ethanol | Insoluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | NU7026 is a potent DNA-PK inhibitor with IC50 of 0.23 μM in cell-free assays, 60-fold selective for DNA-PK than PI3K and inactive against both ATM and ATR. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This
product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |