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NU7026

Product #: TS0066
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Details

l  General Information

Product Name

NU7026

General description

NU7026 is a potent DNA-PK inhibitor.

Synonym

2-morpholin-4-ylbenzo[h]chromen-4-one; LY293646

Purity

≥98.0%(HPLC)

CAS Number

154447-35-5

Formula

C17H15NO3

Molecular Weight

281.311

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

solid

Solubility(25℃)

DMSO

~1mg/mL

Ethanol

Insoluble

Water

Insoluble

l  Biological Information

Biochem/Physiol  Actions

NU7026 is a potent DNA-PK inhibitor with IC50 of 0.23 μM in cell-free assays, 60-fold selective for DNA-PK than PI3K and inactive against both ATM and ATR.

l  Storage

Storage temp.

-20℃

l  Precautions and Disclaimer

This  product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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