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Indirubin

Product #: TS0050
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Details

l  General Information

Product Name

Indirubin

General description

Indirubin is a potent cyclin-dependent kinases and GSK-3β inhibitor.

Synonym

(3E)-3-(3-oxo-1H-indol-2-ylidene)-1H-indol-2-one; NSC 105327

Purity

≥98.0%(HPLC)

CAS Number

479-41-4

Formula

C16H10N2O2

Molecular Weight

262.268

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

solid

Solubility(25℃)

DMSO

≥50mg/mL

Ethanol

Insoluble

Water

Insoluble

l  Biological Information

Biochem/Physiol  Actions

Indirubin is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 μM and 0.6 μM.

Application

1. Antibiotics, Antineoplastic.

2. Coloring Agents.

l  Storage

Storage temp.

-20℃

l  Precautions and Disclaimer

This  product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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