l General Information |
Product Name | 3-Methyladenine (3-MA) |
General description | 3-Methyladenine is one of the purines damaged by alkylation and oxidation which can be recognized and excised by the human 3-methyladenine DNA glycosylase (AAG) |
Synonym | 3-methylpurin-6-amine; NSC 66389 |
Purity | ≥98.0%(HPLC) | CAS Number | 5142-23-4 |
Formula | C6H7N5 | Molecular Weight | 149.15 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | solid |
Solubility(25℃) | DMSO | ~3mg/mL(warmed) |
Ethanol | ~4mg/mL |
Water | ≥10mg/mL(warmed) |
l Biological Information |
Biochem/Physiol
Actions | 3-methyladenine is a methyladenine that is adenine substituted with a methyl group at position N-3. It has a role as a human metabolite and an autophagy inhibitor. 3-Methyladenine is one of the purines damaged by alkylation and oxidation which can be recognized and excised by the human 3-methyladenine DNA glycosylase (AAG) |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This
product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
