l General Information |
Product Name | AS-605240 |
General description | AS-605240 is a selective inhibitor of PI3Kγ. |
Synonym | (5E)-5-(quinoxalin-6-ylmethylidene)-1,3-thiazolidine-2,4-dione |
Purity | ≥98.0%(HPLC) | CAS Number | 648450-29-7 |
Formula | C12H7N3O2S | Molecular Weight | 257.27 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | solid |
Solubility(25℃) | DMSO | Very slightly soluble |
Ethanol | Insoluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | AS-605240 selectively inhibits PI3Kγ with IC50 of 8 nM, over 30-fold and 7.5-fold more selective for PI3Kγ than PI3Kδ/β and PI3Kα in cell-free assays, respectively. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This
product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
