l General Information |
Product Name | Desloratadine |
General description | Desloratadine is a potent antagonist for human histamine H1 receptor with IC50 of 51 nM. |
Synonym | SCH-34117, NSC 675447 |
Purity | ≥98.0%(HPLC) | CAS Number | 100643-71-8 |
Formula | C19H19ClN2 | Molecular Weight | 310.825 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Off-white or beige powder |
Solubility(25°C) | DMSO | ≥15mg/mL |
Ethanol | ≥50mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | Desloratadine is a long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Desloratadine diminishes the typical histaminergic effects on H1-receptors in bronchial smooth muscle, capillaries and gastrointestinal smooth muscle, including vasodilation, bronchoconstriction, increased vascular permeability, pain, itching and spasmodic contractions of gastrointestinal smooth muscle. Desloratadine is used to provide symptomatic relieve of allergic symptoms. |
l Storage |
Storage temp. | 0-5°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
