l General Information |
Product Name | Larotrectinib (LOXO-101) |
General description | Larotrectinib is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C). |
Purity | ≥98.0%(HPLC) | CAS Number | 1223403-58-4 |
Formula | C21H22F2N6O2 | Molecular Weight | 428.4 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Pale yellow to yellow Solid |
Solubility(25°C) | DMSO | ≥4mg/mL |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
