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Ponatinib
TL1155-10MG
In-stock
90
- +
TL1155-50MG
270
TL1155-250MG
760
l General Information
Product Name
General description
Ponatinib is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM in cell-free assays, respectively.
Synonym
AP24534
Purity
≥99.0%(HPLC)
CAS Number
943319-70-8
Formula
C29H27F3N6O
Molecular Weight
532.56
Suitability
BioReagent, suitable for cell culture, etc.
l Physical and Chemical Information
Appearance
yellow powder
Solubility(25°C)
DMSO
≥50mg/mL
Ethanol
Very slightly soluble
Water
Insoluble
l Storage
Storage temp.
-20°C
l Precautions and Disclaimer
This product is for R&D use only, not for drug, household, or other uses.
l References
1. http://www.drugbank.ca
2. https://ncit.nci.nih.gov
3. https://www.ncbi.nlm.nih.gov