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Ponatinib

Product #: TL1155
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l  General Information

Product Name

Ponatinib

General description

Ponatinib is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM in cell-free assays, respectively.

Synonym

AP24534

Purity

≥99.0%(HPLC)

CAS Number

943319-70-8

Formula

C29H27F3N6O

Molecular Weight

532.56

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

yellow powder

Solubility(25°C)

DMSO

≥50mg/mL

Ethanol

Very slightly soluble

Water

Insoluble

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not  for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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