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Baricitinib

Product #: TL1153
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l  General Information

Product Name

Baricitinib

General description

Baricitinib is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM in cell-free assays, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2.

Synonym

LY3009104, INCB028050

Purity

≥99.0%(HPLC)

CAS Number

1187594-09-7

Formula

C16H17N7O2S

Molecular Weight

371.42

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Off-white to light brown powder

Solubility(25°C)

DMSO

≥50mg/mL

Ethanol

Very slightly soluble

Water

Insoluble

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not  for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov


 


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