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Benztropine mesylate

Product #: TL1130
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Details

l  General Information

Product Name

Benztropine mesylate

General description

Benztropine mesylate is a dopamine transporter (DAT) inhibitor with IC50 of 118 nM.

Synonym

(1S,5R)-3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane; methanesulfonic acid

Purity

≥95.0%(HPLC)

CAS Number

132-17-2

Formula

C22H29NO4S

Molecular Weight

403.537

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

white to beige solid

Solubility(25°C)

DMSO

≥45mg/mL

Ethanol

≥50mg/mL

Water

≥50mg/mL

l  Biological Information

Biochem/Physiol  Actions

Benztropine Mesylate is a synthetic antiparkinson tertiary amine structurally related to atropine, Benztropine Mesylate acts as a central muscarinic antagonist and inhibits dopamine uptake. With antihistaminic and local anesthetic properties as well, it is indicated for symptomatic relief of parkinsonism and drug-induced extrapyramidal reactions.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not  for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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