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Diphemanil mesylate

Product #: TL1121
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l  General Information

Product Name

Diphemanil Methylsulfate

General description

Diphemanil Methylsulfate is a quaternary ammonium anticholinergic, it binds muscarinic acetycholine receptors (mAchR).

Synonym

4-benzhydrylidene-1,1-dimethylpiperidin-1-ium;methyl sulfate

Purity

≥98.0%(HPLC)

CAS Number

62-97-5

Formula

C21H27NO4S

Molecular Weight

389.51

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White Crystals

Solubility(25°C)

DMSO

≥15mg/ml

Ethanol

Insoluble

Water

≥5mg/ml

l  Biological Information

Biochem/Physiol  Actions

Diphemanil methylsulfate is the alkene resulting from the formal Wittig olefination of benzophenone and 1,1-dimethyl-4 bromopiperidinium methylsulfate. A quaternary ammonium anticholinergic, it binds muscarinic acetycholine receptors and thereby decreases secretory excretion of stomach acids, saliva and sweat, It is used topically in the treatment of hyperhidorsis (excessive sweating). It has a role as a muscarinic antagonist, a parasympatholytic and a bronchodilator agent. It is a quaternary ammonium salt and a member of piperidines.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not  for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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