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Anagrelide

Product #: TL1102
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Details

l  General Information

Product Name

Anagrelide

General description

Anagrelide is a Platelet-reducing Agent. The mechanism of action of anagrelide is as a Phosphodiesterase 3 Inhibitor.

Purity

≥98.0%(HPLC)

CAS Number

68475-42-3

Formula

C10H7Cl2N3O

Molecular Weight

256.09

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White or off-white to pale yellow solid

l  Biological Information

Biochem/Physiol  Actions

Anagrelide is a drug used for the treatment of essential thrombocytosis (ET; essential thrombocythemia). It works by inhibiting the maturation of megakaryocytes into platelets. Although its exact mechanism of action is not fully understood, it is proposed to primarily work by inhibiting the phosphodiesterase-III enzyme.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not  for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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