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Proparacaine hydrochloride

Product #: TL1095
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l  General Information

Product Name

Proparacaine HCl

General description

Proparacaine HCl is a voltage-gated sodium channels antagonist with ED50 of 3.4 mM.

Synonym

2-(diethylamino)ethyl 3-amino-4-propoxybenzoate; hydrochloride

Purity

≥98.0%(HPLC)

CAS Number

5875-06-9

Formula

C16H27ClN2O3

Molecular Weight

330.853

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White or off-white solid

Solubility(25°C)

DMSO

≥5m/ml

Ethanol

≥25mg/ml

Water

≥50mg/ml

l  Biological Information

Biochem/Physiol  Actions

Proparacaine Hydrochloride is the hydrochloride salt form of proparacaine, a benzoic acid derivative with local anesthetic property. Proparacaine hydrochloride stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting sodium ion influx required for the initiation and conduction of impulses within the neuronal cell, and resulting in a loss of sensation.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not  for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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