Product Name

Estradiol Cypionate

General description

Estradiol cypionate is the 17 β-cyclopentylpropinate ester of estradiol, which inhibits ET-1 synthesis via estrogen receptor.

Purity

≥99.0%(HPLC)

CAS Number

313-06-4

Formula

C²⁶H³⁶O³

Molecular Weight

396.571

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

white to off-white solid

Solubility(25°C)

DMSO

≥45mg/ml

Ethanol

≥35mg/ml

Water

Insoluble

l  Biological Information

Biochem/Physiol  Actions

Estradiol Cypionate is the cypionate salt form of estradiol, the most potent, naturally produced estrogen. Estradiol cypionate diffuses through the cell membrane and binds to and subsequently activates the nuclear estrogen receptor found in the reproductive tract, breast, pituitary, hypothalamus, liver, and bone. The activated complex binds to the estrogen response element on the DNA and activates the transcription of genes involved in the functioning of the female reproductive system and secondary sex characteristics.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not  for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov