Product Name

Dantrolene sodium

General description

Dantrolene sodium acts as a postsynaptic muscle relaxant by inhibiting Ca₂₊ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors.

Purity

≥98.0%(HPLC)

CAS Number

14663-23-1

Formula

C¹⁴H⁹N⁴NaO⁵

Molecular Weight

336.23

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Orange yellow solid

Solubility(25°C)

DMSO

≥50mg/mL

l  Biological Information

Biochem/Physiol  Actions

A heterogeneous group of drugs used to produce muscle relaxation, excepting the neuromuscular blocking agents. They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. They have been used also for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in MULTIPLE SCLEROSIS.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not  for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov