l General Information |
Product Name | Eprodisate disodium |
General description | Eprodisate Disodium is the orally available disodium salt form of Eprodisate, a small-molecule, orally bioavailable, inhibitor of AA-amyloid fibrillogenesis. |
Synonym | NC-503; disodium;propane-1,3-disulfonate |
Purity | ≥99.0%(TLC) | CAS Number | 36589-58-9 |
Formula | C3H6Na2O6S2 | Molecular Weight | 248.19 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to Off White solid |
Solubility(25°C) | DMSO | Insoluble |
Ethanol | Insoluble |
Water | ≥35mg/ml |
l Biological Information |
Biochem/Physiol
Actions | Eprodisate Disodium is the orally available disodium salt form of eprodisate, a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis. Upon administration, eprodisate competitively binds to the glycosaminoglycan binding sites on serum amyloid A (SAA), which inhibits the formation of the glycosaminoglycan-amyloid fibril aggregate. This prevents the formation of amyloid deposits in certain organs, especially the kidneys, in AA amyloidosis. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not
for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
