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Maprotiline hydrochloride

Product #: TL1054
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l  10347-81-6General  Information

Product Name

Maprotiline HCl

General description

Maprotiline HCl is a selective noradrenalin re-uptake inhibitor, used in the treatment of depression.

Synonym

N-methyl-3-(1-tetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaenyl)propan-1-amine; hydrochloride

Purity

≥98.0%(HPLC)

CAS Number

10347-81-6

Formula

C20H24ClN

Molecular Weight

313.869

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to Off White solid

Solubility(25°C)

DMSO

≥50mg/mL

Ethanol

≥15mg/mL

Water

Insoluble

l  Biological Information

Biochem/Physiol  Actions

Maprotiline Hydrochloride is the hydrochloride salt form of maprotiline, a tetracyclic antidepressant closely related to the tricyclic antidepressants with adrenergic activity and sedative properties. Maprotiline hydrochloride exerts its effect by blocking the re-uptake of norepinephrine, thereby increasing the synaptic concentration of norepinephrine in the central nervous system and subsequently prolonging the action of norepinephrine on central receptors.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not  for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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