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Prochlorperazine Maleate

Product #: TL1048
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l  General Information

Product Name

Prochlorperazine dimaleate salt

General description

Prochlorperazine dimaleate is a dopamine (D2) receptor antagonist.

Synonym

Prochlorperazin, Compazine, Capazine, Stemetil

Purity

≥99.0%(HPLC)

CAS Number

84-02-6

Formula

C28H32ClN3O8S

Molecular Weight

606.09

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Pale yellow or yellow green solid

Solubility(25°C)

DMSO

≥45mg/ml

Ethanol

Slightly soluble

Water

Insoluble

l  Biological Information

Biochem/Physiol  Actions

Prochlorperazine Maleate is the maleate salt form of prochlorperazine, a synthetic, piperazinephenothiazine derivative with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Prochlorperazine binds to and blocks the postsynaptic dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy induced emesis. Prochlorperazine maleate also blocks anticholinergic and alpha-adrenergic receptors. Its antagonistic actions on the alpha-1 adrenergic receptors results in sedation, muscle relaxation, and hypotension.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not  for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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