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Nitroxoline

Product #: TL1046
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l  General Information

Product Name

Nitroxoline

General description

Nitroxoline is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections. It is a fluorquinolone that is active against bacterial gyrases.

Synonym

8-Hydroxy-5-nitroquinoline, 5-nitroquinolin-8-ol, 5-Nitro-8-quinolinol|5-Nitro-8-hydroxyquinoline, 5-nitroquinolin-8-ol

Purity

≥99.0%(HPLC)

CAS Number

4008-48-4

Formula

C9H6N2O3

Molecular Weight

190.16

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Light Yellow to Dark Yellow or brown solid

Solubility(25°C)

DMSO

≥25mg/ml

Ethanol

Insoluble

Water

Insoluble

l  Biological Information

Biochem/Physiol  Actions

Nitroxoline is a monohydroxyquinoline in which the hydroxy group is positioned at C-8 with a nitro group trans to it at C-5. It has a role as an antimicrobial agent, an antifungal agent, a renal agent and an antiinfective agent. It is a C-nitro compound and a monohydroxyquinoline.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not  for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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