Product Name

Cinchocaine

General description

Cinchocaine is a potent and long-acting local anesthetics used for surface anesthesia.

Synonym

Dibucaine;  2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide 

Purity

≥99.0%(HPLC)

CAS Number

85-79-0

Formula

C²⁰H²⁹N³O²

Molecular Weight

343.46

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Off-white or pale yellow solid

Solubility(25°C)

DMSO

≥50mg/ml

l  Biological Information

Biochem/Physiol  Actions

Dibucaine is a quinoline derivative and amino amide with anesthetic activity. Dibucaine reversibly binds to and inactivates sodium channels in the neuronal cell membrane. Inhibition of sodium channels prevents the depolarization of nerve cell membranes and inhibits subsequent propagation of impulses along the course of the nerve, thereby limiting the excitation of nerve endings. This results in loss of sensation.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not  for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov