Product Name

Methylene Blue trihydrate

General description

Methylene blue is used as a bacteriologic stain or dye and indicator.

Synonym

3,7-bis(Dimethylamino)phenazathionium chloride, Basic Blue 9, Tetramethylthionine chloride

Dye content

≥82%

CAS Number

7220-79-3

Formula

C¹⁶H²⁴ClN³O³S

Molecular Weight

373.9

Suitability

Certified for use in Mallory′s phloxine-methylene blue stain; Levine & Black stain for bacteria in milk; Wright stain for blood smears.

l  Physical and Chemical Information

Appearance

Brown solid

l  Biological Information

Biochem/Physiol  Actions

Methylene blue is used as a bacteriologic stain or dye and indicator. It mediates the inactivation of enveloped viruses in plasma, when exposed to visible light. It is an inhibitor of nitric oxide synthase and guanylate cyclase. It also plays a key role in medicine as an antimalarial agent, reducing agent in methemoglobinemia and inducer of apoptosis in cancer cells.

Application

Methylene blue has been used:

•  to stain vaginal cells

•  for the preparation of protein aqueous ink

•  to evaluate cell survival by staining

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not  for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov