Product Name

Sulfacetamide sodium salt hydrate

General description

Sulfacetamide sodium salt hydrate is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase(DHPS) with IC50 of 9.5 μM. Sulfacetamide is a competitive inhibitor of bacterial para aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid.

Synonym

sodium;acetyl-(4-aminophenyl)sulfonylazanide; hydrate

Purity

≥99.0%(HPLC)

CAS Number

6209-17-2

Formula

C⁸H¹¹N²NaO⁴S

Molecular Weight

254.24

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to off-white solid

Solubility(25°C)

DMSO

≥35mg/ml

Ethanol

Slightly soluble

Water

≥35mg/ml

l  Biological Information

Biochem/Physiol  Actions

Sulfacetamide Sodium is the sodium salt form of sulfacetamide, a synthetic sulfanylacetamide derivative with bacteriostatic activity. Sulfacetamide inhibits bacterial folic acid synthesis by competing with para amino benzoic acid. With a broad spectrum of action, it is used as an anti-infective topical agent to treat skin infections and as an oral agent for urinary tract infections.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not  for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov